I might end up doing it sooner then I thought. If I manage to swing it before you I'll post the results here.
In all seriousness the easiest way to find out would be to close or block the vent and give it a couple of hours.
I intend to make the return vent active by using an inline fan unit. I will be setting it up to turn on with the main central air fan probably with a relay powered through a step-down transformer from the C/A power tap. This will avoid stringing wire running 220V/120V half way through the attic.